General Information About Addison's Disease
Addison's disease (primary adrenal insufficiency) is a rare endocrine disorder that occurs when the adrenal glands are damaged, leading to the insufficient production of cortisol and aldosterone hormones. Disrupting the body's response to stress and salt-water balance, this disease manifests with chronic fatigue, weight loss, and skin darkening.
Disease Details and Frequently Asked Questions
You can find detailed information about the condition under the headings below.
What is Addison's Disease?
It is a health condition characterized by a deficiency of cortisol and aldosterone hormones as a result of the underfunctioning of the adrenal glands.
What Causes It?
It mostly occurs when the immune system attacks the adrenal glands (autoimmune causes), or when the glands are damaged due to infections or hemorrhages.
What are the Symptoms?
Chronic fatigue, muscle weakness, loss of appetite, weight loss, low blood pressure, and specifically darkening of the skin (hyperpigmentation), especially around gums and scars, are observed.
What is an Addisonian Crisis?
It is the sudden experience of severe hormone deficiency in the body during periods of extreme physical stress, infection, or trauma. It is life-threatening and requires immediate emergency intervention.
How is it Diagnosed?
Cortisol, ACTH, and sodium/potassium levels in the blood are checked. When necessary, an ACTH stimulation test and radiological imaging of the adrenal glands are performed.
How is it Treated?
By externally supplementing the deficient cortisol and aldosterone hormones in pill form for life, the patient can lead a completely normal life.
Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.
