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Ankylosing Spondylitis

Diagnosis, symptoms, and treatment methods.

General Information About Ankylosing Spondylitis

Ankylosing Spondylitis is a progressive rheumatic disease that causes chronic inflammation, especially in the joints of the spine and pelvis. Inflamed vertebrae fuse together over time, causing the spine to lose its flexibility and take on a 'bamboo spine' appearance. In our Rheumatology clinic, the progression of the disease is stopped and the patient's mobility is preserved with biological agents and physiotherapy supports.

Disease Details and Frequently Asked Questions

You can find detailed information about the condition under the headings below.
What is Ankylosing Spondylitis?

It is a chronic inflammatory disease where the immune system attacks the joint and connective tissues connecting the spine, which, if left untreated, causes the vertebrae to fuse.

What is the Difference from a Mechanical Herniated Disc?

Hernia pain increases with movement and standing, and resolves with rest. Conversely, Ankylosing Spondylitis (Inflammatory rheumatism) pain increases with rest (while lying down at night), one wakes up with a stiff lower back in the morning, and the pain decreases with movement/exercise.

What Causes It and Who Does It Affect?

Although the exact cause of the disease is unknown, genetic predisposition is very strong. The HLA-B27 gene is positive in the vast majority of patients. The disease usually appears in young men between the ages of 15-30.

Which Organs Does It Affect Other Than the Spine?

It does not only affect the lower back and back. It can be accompanied by recurrent redness and pain in the eye (Uveitis), heel spurs (Achilles tendinitis), restriction in the rib cage, and intestinal inflammations (Crohn's, etc.).

How is it Diagnosed?

A detailed rheumatological examination is conducted, looking at blood inflammation levels (CRP) and the HLA-B27 gene test. To detect inflammation in the pelvic joints (sacroiliitis) at an early stage, a Pelvic MRI is performed.

How is it Treated?

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to stop the inflammation. In advanced cases, targeted immunosuppressive 'Biological Agent' injections are prescribed. Regular daily stretching exercises and swimming are an inseparable part of the treatment.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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