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Behçet's Disease

Diagnosis, symptoms, and treatment methods.

General Information About Behçet's Disease

Behçet's disease is a systemic syndrome where the immune system causes chronic inflammation (vasculitis) in the body's blood vessels for an unknown reason. Recurrent oral aphthae, genital ulcers, and eye inflammation (uveitis) form the primary triad of the disease. As a multidisciplinary disease, Behçet's is kept under control with immunosuppressive drugs through the joint efforts of our Rheumatology, Ophthalmology, and Dermatology clinics.

Disease Details and Frequently Asked Questions

You can find detailed information about the disease under the headings below.
What is Behçet's Disease?

It is an autoimmune vascular inflammation (vasculitis) disease that can affect arteries and veins of all sizes in the body, causing inflammation in vessel walls and leading to organ damage.

In Whom and at What Ages is it Commonly Seen?

It is especially common in countries along the historical 'Silk Road', including Turkey, the Middle East, and the Far East. It usually begins in young adults in their 20s and 30s.

What Are Its Most Classic Symptoms?

Recurrent painful oral aphthae (at least 3 times a year), ulcers around the genital area that heal with scarring, and painful acne-like bumps on the skin (erythema nodosum).

How Does It Damage the Eye?

It causes inflammation in the inner layers of the eye (Uveitis), leading to redness, blurred vision, and pain. If left untreated, it can progress in attacks and lead to permanent blindness.

How is it Diagnosed?

There is no specific blood test. Clinical symptoms are evaluated. To support the diagnosis, a 'Pathergy Test' is performed, where the forearm is pricked with a needle, and the formation of a red bump/pustule in that area is checked after 48 hours.

How is it Treated?

There is no cure that completely eradicates the disease. Corticosteroids, colchicine, and strong immunosuppressive drugs are used to prevent attacks and stop organ damage.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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