General Information About Budd-Chiari Syndrome
Disease Details and Frequently Asked Questions
It is the condition where blood is trapped inside the liver, causing the organ to swell, as a result of the blockage of the main veins (hepatic veins) that carry blood out of the liver back to the heart.
In the vast majority of cases, the underlying cause is genetic blood disorders that increase the tendency to clot in the blood (Thrombophilia, etc.). Additionally, oral contraceptive use, pregnancy, and tumor pressure can also block the vein.
Because the liver fills with blood and swells, severe pain in the upper right abdomen, severe fluid accumulation in the abdominal cavity called ascites, jaundice, and enlargement of the liver (hepatomegaly) are the most prominent complaints.
Yes. Because the blood cannot exit the liver, the internal pressure of the organ increases, and the entry of fresh blood is also prevented. Deprived of oxygen, the liver cells die over time, leading to cirrhosis and acute liver failure.
It is suspected when Doppler Ultrasonography shows that blood flow in the liver veins has stopped. For a definitive diagnosis, Computed Tomography (CT) or Contrast-Enhanced MR Angiography is performed.
In the early stage, blood-thinning (anticoagulant) medications are given. If the blockage cannot be opened with medication, the vein is entered using an angiographic method and a stent is inserted, or an artificial shunt (channel) called 'TIPS' is created to reduce the pressure in the liver. In very advanced stages, a liver transplant may be required.
Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.
