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Bullous Pemphigoid

Diagnosis, symptoms, and treatment methods.

General Information About Bullous Pemphigoid

Bullous pemphigoid is a rare autoimmune skin disease that develops as a result of the immune system mistakenly attacking the connective tissue beneath the skin, mostly affecting older individuals. It causes severe itching and large fluid-filled blisters (bullae) on the skin. In our Dermatology clinic, the rashes are brought under control by treatment with immunosuppressive systemic corticosteroids and immunosuppressant drugs.

Disease Details and Frequently Asked Questions

You can find detailed information about the disease under the headings below.
What is Bullous Pemphigoid?

It is a chronic skin disease where large, tense, water-filled blisters form on the skin as a result of the body's defense cells attacking the proteins that hold the layers of its own skin together.

Who Gets It?

The disease usually appears in older adults over the age of 60. It is quite rare for it to be seen in children and younger adults.

What Are the Symptoms?

The disease begins with eczema-like redness and severe itching weeks before the blisters appear. Later, tense fluid collections (bullae) that are hard to pop occur on the arms, legs, and abdomen.

Is It a Contagious Disease?

Absolutely not. Since bullous pemphigoid is not caused by an infection (germs), it is not transmitted from person to person through touching or sharing the same items.

How is it Diagnosed?

A small piece is taken from the lesioned skin by a dermatology specialist (biopsy), and a definitive diagnosis is made in the laboratory using a special staining technique called Direct Immunofluorescence (DIF) to detect autoantibodies under the skin.

How is it Treated?

Depending on the severity of the disease, creams containing high doses of cortisone (steroid) or oral cortisone pills are started. In long-term treatment, other immune-regulating drugs (immunosuppressants) are added to the treatment to reduce the side effects of cortisone.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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