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Celiac Disease

Diagnosis, symptoms, and treatment methods.

General Information About Celiac Disease

Celiac disease is an autoimmune condition in genetically predisposed individuals where the immune system reacts abnormally to the protein 'Gluten' found in wheat, barley, and rye, thereby destroying the nutrient-absorbing surface (villi) in the small intestines. It presents with bloating, diarrhea, and anemia. After a definitive diagnosis is made in our Gastroenterology clinic, the disease can be entirely controlled with a strict gluten-free diet program.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Celiac Disease?

It is a systemic disease where the body initiates an allergic/autoimmune attack against a protein called gluten, flattening the microscopic brush-like structures (villi) on the inner lining of the small intestine where nutrients are absorbed.

Is It Just a Gastrointestinal Problem?

No. Because the intestines cannot absorb nutrients, the individual becomes deficient in vitamins and iron regardless of what they eat. This leads to systemic issues such as anemia, osteoporosis, short stature in children, infertility, and skin rashes.

What are the Symptoms?

Symptoms include severe abdominal bloating that starts after consuming gluten, gas, persistent chronic diarrhea or sometimes constipation, abdominal pain, chronic fatigue, and unexplained weight loss.

Is It the Same as Gluten Sensitivity?

In gluten sensitivity, the individual feels bloating and discomfort upon eating gluten, but their small intestines are not physically destroyed. In celiac disease, there is physical destruction and an autoimmune attack.

How is it Diagnosed?

Initially, blood tests are performed to check for Celiac-specific antibodies (Anti-Tissue Transglutaminase). If the blood test is positive, an Endoscopy is performed under anesthesia for definitive diagnosis; a biopsy (tissue sample) is taken from the small intestine, and the destruction of the villi is confirmed via pathology.

How is it Treated? Is There a Cure with Medication?

There is no medical drug for the disease. The only and definitive treatment is to follow a 100% Gluten-Free Diet for life. When the diet is adhered to, the intestines completely repair themselves, and all complaints disappear.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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