General Information About Erythema Multiforme
Disease Details and Frequently Asked Questions
It is a skin disease with distinctly shaped rashes that suddenly appear on the skin as a result of the immune system developing a reaction to an infection or external factor.
In about 90% of cases, the triggering cause is Herpes Simplex Virus (cold sore virus) infections. Additionally, certain antibiotics, painkillers, and mycoplasma bacteria can also initiate these rashes.
It is the most typical finding of the disease. The lesions that appear on the skin look exactly like an archery target, with a dark red/purple spot in the center, surrounded by a pale ring, and an outermost red ring.
The rashes appear symmetrically on both arms, the backs of the hands, the palms, and the soles of the feet. This skin disease is not contagious; it does not spread from person to person through contact.
A clinical examination by a dermatologist and the typical target-like shape of the rashes are usually sufficient to make a diagnosis. In doubtful cases, a small skin biopsy can be taken.
The triggering factor is eliminated (stopping the medication if it is a drug, or using antivirals if it is a virus). Antihistamine pills and topical cortisone creams are applied to relieve the itching and mild burning caused by the rashes; the disease heals without leaving scars within 2-4 weeks.
Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.
