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Graves' Disease

Diagnosis, symptoms, and treatment methods.

General Information About Graves' Disease

Graves' disease is an autoimmune disorder where the immune system overstimulates the thyroid gland, causing it to produce excessive amounts of hormones (hyperthyroidism). Palpitations, weight loss, and bulging eyes (exophthalmos) are its most typical findings. In our Endocrinology clinic, it is controlled with antithyroid drugs, radioactive iodine therapy, and surgical methods when necessary.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Graves' Disease?

It is the condition where abnormal antibodies produced by the body's immune system continuously stimulate the thyroid gland in the neck, causing the gland to grow uncontrollably and secrete (excessive) thyroid hormone.

What is the Difference from Toxic Goiter?

Toxic goiter (Hyperthyroidism) is a general condition where thyroid hormone is excessive. Graves' disease, on the other hand, is the most common underlying disease that causes this hyperthyroidism condition.

What are the Symptoms?

Rapid weight loss despite eating a lot, visible shaking (tremors) in the hands, intolerance to heat, continuous sweating, insomnia, severe palpitations, and nervousness.

Why Does It Affect the Eyes (Ophthalmopathy)?

The same antibodies produced by the immune system also attack the muscles and fat tissues behind the eye. The inflammation and swelling of these tissues push the eyeball forward, causing a startled (bulging) appearance (exophthalmos).

How is it Diagnosed?

A blood test will show that the TSH hormone is suppressed, while T3 and T4 hormones are very high. A definitive diagnosis is made by detecting Graves-specific (TRAb) antibodies in the blood and via Thyroid Ultrasound/Scintigraphy.

How is it Treated?

Special antithyroid medications that stop hormone synthesis are started, and beta-blockers are added to lower the heart rate. In cases that do not respond to medication or recur, radioactive iodine (atomic therapy) or the complete surgical removal of the thyroid gland is preferred.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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