General Information About Hemolytic Anemia
Disease Details and Frequently Asked Questions
It is the condition where healthy blood cells entering circulation are rapidly and uncontrollably destroyed by external factors or antibodies, despite there being no problem in the blood production center (bone marrow).
It occurs as a result of autoimmune reactions where the immune system attacks the blood as an enemy (most common), mechanical heart valves crushing the blood, severe infections (such as malaria), and the side effects of certain medications (such as penicillin).
Dizziness, palpitations, and fatigue are seen because the blood's oxygen-carrying capacity decreases. The most typical distinguishing feature is Jaundice (Icterus) in the eyes and skin, and urine taking on the color of tea, due to the bilirubin substance released from the broken down blood cells.
The spleen is the organ where blood is filtered and aged cells are destroyed. The cell destruction becomes so rapid and massive that the overworked spleen grows over time (Splenomegaly), reaching a size that fills the abdomen.
A complete blood count reveals anemia and a high level of reticulocytes, indicating the rate of blood cell production. The test that proves whether the disease is immune-mediated (autoimmune) is the 'Direct Coombs Test'.
Taking iron supplements does not cure this disease. To stop the destruction, high-dose Cortisone pills or IVIG serums are started first. If the disease cannot be controlled with medication, the primary center of destruction, the spleen, is surgically removed (Splenectomy) to provide a cure.
Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.
