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HSP (Henoch-Schönlein Purpura) Disease

Diagnosis, symptoms, and treatment methods.

General Information About HSP

Henoch-Schönlein Purpura (HSP) is a disease that develops as a result of inflammation (vasculitis) of small blood vessels mediated by IgA antibodies belonging to the immune system. Mostly in children, it presents with purple rashes on the legs, joint, and abdominal pain following an upper respiratory tract infection. In our Pediatric Rheumatology department, it is monitored for kidney involvement and managed with supportive treatments.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is HSP (Henoch-Schönlein Purpura)?

It is a disease where IgA type defense proteins produced by the immune system accumulate in small blood vessels in the skin, joints, intestines, and kidneys, causing inflammation (vasculitis).

What Causes It?

Although the exact cause is unknown, in most cases, a bacterial or viral upper respiratory tract infection (like the flu or strep throat) experienced a few weeks before the onset of the disease acts as a trigger.

What is the Characteristic of the Rashes (Purpura)?

It is the signature feature of the disease. They are slightly raised red-purple bleeding spots, usually appearing on the legs, buttocks, and ankles, that do not pale (disappear) when pressed with a glass.

Does It Only Affect the Skin?

No. Along with the rashes; it is accompanied by swelling/pain in the knees and ankles (arthritis), severe abdominal cramps due to intestinal bleeding, and kidney inflammation (nephritis) manifesting as blood in the urine.

How is it Diagnosed?

It is diagnosed clinically by a doctor evaluating the classic rashes, joint, and abdominal complaints together. A urinalysis is performed to measure kidney damage, and a blood count to rule out infections.

How is it Treated?

The disease usually heals completely on its own within 4-6 weeks. Treatment is supportive; painkillers (NSAIDs) for joint and abdominal pain, or corticosteroid drugs in severe cases/kidney involvement are applied.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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