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Inflammatory Bowel Disease (IBD)

Diagnosis, symptoms, and treatment methods.

General Information About Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is the general name for autoimmune diseases where the immune system perceives the digestive system as an enemy, causing chronic inflammation and non-healing ulcers. The two most well-known types are Crohn's disease and Ulcerative Colitis. It progresses with bloody diarrhea and abdominal cramps. In our Gastroenterology clinic, it is diagnosed through colonoscopy and controlled with immunosuppressants and biological (smart) medications.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Inflammatory Bowel Disease (IBD)?

It is the permanent redness, swelling, and ulceration (open sores) of the cells lining the inner surface of the digestive system (from the mouth to the anus) due to an overactive immune system response.

What is the Difference Between Crohn's Disease and Ulcerative Colitis?

Ulcerative Colitis is a continuous inflammation that only affects the large intestine and its surface layer. Crohn's Disease, however, is a patchy inflammation that can affect any part of the digestive tract from the mouth to the anus and can penetrate all layers of the bowel.

What are the Symptoms?

Severe cramp-like abdominal pain that comes in attacks (flare-ups), bloody and mucous diarrhea recurring many times a day, fever episodes, anemia, and severe involuntary weight loss.

Does It Affect Organs Outside the Bowel?

Yes. Because the disease enters the bloodstream, it causes damage outside the bowel as well. Recurrent redness in the eyes (uveitis), swelling in the joints (arthritis), large sores on the skin (Erythema Nodosum), and inflammation in the liver ducts can be seen.

How is it Diagnosed?

Occult blood in the stool and Calprotectin levels, which indicate bowel inflammation, are checked. A definitive distinction and diagnosis are made by taking a tissue sample (biopsy) from the bowel during a Colonoscopy performed under anesthesia.

How is it Treated?

The goal is to promote healing of the bowel. Cortisone, mesalazine suppositories, and immunosuppressive drugs are used. In severe cases that do not respond, TNF inhibitors (Biological Agents) are applied. If the damage to the bowel is irreversible, the diseased bowel is completely removed surgically.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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