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Insulin Resistance

Diagnosis, symptoms, and treatment methods.

General Information About Insulin Resistance

Insulin resistance is a condition where the body's cells become desensitized to the insulin hormone secreted by the pancreas, making them unable to absorb glucose (sugar) into the cell. This forces the pancreas to produce more insulin and paves the way for Type 2 diabetes over time. In our Internal Medicine and Nutrition departments, its treatment and follow-up are carried out with medical nutrition, exercise, and medication support.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Insulin Resistance?

It is the condition where the cells' doors are closed to the insulin hormone, resulting in the sugar in the blood being unable to enter the cells to be used as energy, thus starting to accumulate in the blood.

Why Does It Occur?

Excess weight (especially abdominal fat), a sedentary lifestyle, and a diet high in refined sugar and carbohydrates disrupt insulin receptors and trigger resistance.

What are the Symptoms?

Sudden sleepiness after meals (especially carbohydrates), a constant desire (craving) to eat sweets, difficulty losing weight, thickening around the waist, and chronic fatigue.

What is Darkening of the Neck (Acanthosis Nigricans)?

Excessively elevated insulin levels in the blood cause abnormal proliferation of skin cells, creating dark brown/black patches that look like dirt on the back of the neck, armpits, and groin.

How is it Diagnosed?

It is diagnosed using a mathematical formula called the HOMA-IR index (over 2.5 indicates resistance), based on Fasting Blood Sugar and Fasting Insulin levels taken from blood on an empty stomach in the morning.

How is it Treated?

It requires lifestyle changes rather than medication. A low glycemic index diet where simple sugars are cut out, regular exercise (muscles burn sugar without insulin), and weight loss completely break the resistance. If necessary, drugs like metformin are given as support.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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