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ITP Disease

Diagnosis, symptoms, and treatment methods.

General Information About ITP Disease

ITP (Immune Thrombocytopenic Purpura) is an autoimmune blood disorder where the immune system mistakenly attacks and destroys platelets, which are responsible for blood clotting. It presents with unexplained bruising on the skin, petechiae, and bleeding gums. In hematology departments, it is brought under control with corticosteroids, IVIG therapies, or the surgical removal of the spleen.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is ITP Disease?

It is a condition where platelet cells, responsible for stopping bleeding, are perceived as an enemy by the body's own immune system and destroyed in the spleen, causing their numbers to fall to dangerous levels.

What are the Symptoms?

Spontaneous bruising on the skin without trauma, pinhead-sized red rashes on the legs (petechiae), unstoppable nosebleeds, bleeding gums, and excessively long/heavy menstrual bleeding in women.

Why Does It Occur?

The exact cause is unknown. However, in children, it usually begins as an antibody response developed by a confused immune system a few weeks after a simple viral infection (like the flu).

What is the Course in Children and Adults?

ITP in children usually has an acute course and resolves completely within a few months, either without treatment or with short-term therapy. In adults, it mostly turns into a chronic lifelong disease.

How is it Diagnosed?

It is suspected when red and white blood cells are completely normal in a Complete Blood Count (Hemogram), but the platelet count is extremely low (often below 20,000). A bone marrow biopsy may be performed to rule out leukemia.

How is it Treated?

Cortisone (steroid) pills are used for mild bleeding. If there is severe and urgent bleeding, high-dose Immunoglobulin (IVIG) is given intravenously. In chronic patients resistant to drugs, the spleen, where platelets are destroyed, may be surgically removed (splenectomy).

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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