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Lupus (Systemic Lupus Erythematosus)

Diagnosis, symptoms, and treatment methods.

General Information About Lupus

Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system attacks its own tissues, causing chronic inflammation in organs such as the skin, joints, kidneys, and brain. The butterfly-shaped rash covering the bridge of the nose and cheeks is its most typical finding. In our Rheumatology unit, the activity of the disease is brought under control with immunosuppressive agents and corticosteroids.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Lupus (Butterfly Disease)?

It is a chronic autoimmune disease in which the body's defense mechanism (the immune system) becomes confused and attacks the person's own healthy tissues, cells, and organs instead of foreign substances.

Why is it Called 'Butterfly' Disease?

It is known by this name because it creates a characteristic red rash (malar rash) in patients (especially when going out in the sun) that starts from the bridge of the nose and spreads to both cheeks, resembling the wings of a butterfly in shape and borders.

What are the Symptoms?

In addition to facial rashes; severe joint pain and swelling, extreme sensitivity to the sun, persistent fatigue, unexplained fever, hair loss, and sores inside the mouth are seen.

Which Organs Does It Harm?

It is a systemic disease, meaning it does not only affect the skin. It can cause its most serious damage in the kidneys (lupus nephritis), leading to kidney failure. It can also affect the lining of the heart (pericarditis) and brain nerves.

How is it Diagnosed?

A clinical evaluation by a rheumatologist is essential. Positive results for ANA (Antinuclear Antibody) and Anti-dsDNA blood tests, which indicate an error in the immune system, are diagnostic.

What is the Treatment?

There is no treatment that completely cures (eradicates) the disease. The goal is to calm the immune system and prevent organ damage. Malaria medications (Hydroxychloroquine), cortisone (steroid) pills, and in severe cases, immunosuppressives or biological drugs are used.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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