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Colitis and Ulcerative Colitis

Diagnosis, symptoms, and treatment methods.

General Information About Colitis and Ulcerative Colitis

Ulcerative colitis is a condition where the mucosa lining the inner surface of the large intestine becomes chronically inflamed and forms bleeding ulcers as a result of a faulty response of the immune system. It is characterized by bloody diarrhea, abdominal cramps, and an urgent need to defecate. In our Gastroenterology clinic, it is diagnosed through colonoscopic examinations and remission is achieved with immunosuppressive agents and biological treatments.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Ulcerative Colitis?

It is a chronic autoimmune disease that affects only the large intestine (colon) and the rectum, causing permanent inflammation, swelling, and bleeding sores (ulcers) on the inner lining of the intestine.

What is the Difference from Crohn's Disease?

While Crohn's disease can affect any part of the digestive tract from the mouth to the anus in a patchy (skip) manner; Ulcerative Colitis occurs only in the large intestine, starting from the anus and progressing continuously.

What are the Symptoms?

Bloody and mucous (slimy) diarrhea that repeats many times a day, severe cramp-like abdominal pain, a constant urge to go to the toilet (tenesmus), anemia, and involuntary weight loss.

Does It Increase the Risk of Cancer?

Yes. Untreated ulcerative colitis, which causes constant inflammation (cell destruction and repair) in the intestine over the years, significantly increases the risk of developing colon cancer after 8-10 years.

How is it Diagnosed?

Levels of occult blood and calprotectin (an inflammation marker) in the stool are checked. For a definitive diagnosis, a Contrast-Enhanced Colonoscopy is performed by a Gastroenterology specialist to visualize the inside of the intestine, and a tissue biopsy is taken from suspicious areas.

How is it Treated?

Corticosteroids, mesalazine-containing enemas, and in advanced cases, smart drugs (biological agents) that regulate the immune system are used to suppress the inflammation. In severe cases where medications do not work, completely removing the large intestine surgically is the definitive solution.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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