General Information About Langerhans Cell Histiocytosis
Disease Details and Frequently Asked Questions
It is the destruction of tissues by cells of the immune system forming tumor-like accumulations.
It lies on a spectrum between cancer and an autoimmune disease. There is cancer-like cell proliferation.
Bone pain, persistent skin rashes, ear discharge, swollen lymph nodes, and excessive urination/diabetes insipidus.
It can involve a single bone, or it can involve multiple organs such as bone marrow, liver, lungs, and the brain.
Bone lesions are detected by X-ray/MRI; definitive diagnosis is made by biopsy taken from the lesion and immunohistochemical staining.
If there is only bone involvement, it may be self-limiting or local curettage is performed. Chemotherapy and cortisone treatment are mandatory in systemic involvement.
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