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Multiple Sclerosis (MS)

Diagnosis, symptoms, and treatment methods.

General Information About MS Disease

Multiple Sclerosis (MS) is a chronic autoimmune disease in which the immune system mistakenly attacks and damages the protective myelin sheath surrounding nerve cells in the central nervous system (brain and spinal cord). Neurological deficits due to slowed conduction, such as vision loss, numbness, and balance issues, present in bouts (attacks). In our neurology clinic, it is detected via MRI and halted through corticosteroid therapies and disease-modifying immunosuppressive medications.

Disease Details and Frequently Asked Questions

Detailed information regarding the disease can be accessed from the headings below.
What is Multiple Sclerosis (MS)?

It is a condition where the body's immune cells erroneously attack and destroy the electrical insulation sheaths (myelin) surrounding nerve fibers in the brain and spinal cord.

What Does an Attack (Relapse) Mean?

In the vast majority of patients (Relapsing-Remitting type), the disease suddenly flares up and neurological deficits are experienced (attack). Weeks after the attack subsides, the body repairs part or all of this damage, and symptoms fade.

What are its Symptoms?

Frequently, the initial symptom is blurred vision or vision loss in the eye (optic neuritis). Additionally, numbness, tingling, loss of strength, electric-shock sensations in the arms/legs, gait and balance disturbances, and profound fatigue are observed.

Why Does It Occur?

The exact cause remains unknown. It is believed that in genetically predisposed individuals, the Epstein-Barr virus (mononucleosis), severe vitamin D deficiency, and smoking act as triggers for the disease.

How is it Diagnosed?

Contrast-enhanced MRI scans of the Brain and Spinal Cord are performed to detect the white plaques (lesions) left by myelin damage. If necessary, a cerebrospinal fluid (CSF) analysis obtained via lumbar puncture is evaluated for oligoclonal bands, indicating immune activity.

How is it Treated?

To immediately halt the damage during an acute attack, very high doses of intravenous corticosteroids are administered. In the long term, lifelong disease-modifying (immunosuppressive) therapies in the form of injections or tablets are utilized to prevent relapses and stop the progression of the disease toward disability.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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