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Prolactinoma

Diagnosis, symptoms, and treatment methods.

General Information About Prolactinoma

Prolactinoma is a benign adenoma (tumor) that develops in the pituitary gland in the brain and produces excessive amounts of the milk-producing hormone, prolactin. It causes menstrual irregularities and breast milk discharge (galactorrhea) in women, and loss of sexual desire in men. In our Endocrinology department, the tumor is successfully shrunk and hormones are balanced using dopamine agonist medications.

Disease Details and Frequently Asked Questions

You can access detailed information about the disease under the headings below.
What is Prolactinoma?

It is a benign tumor (adenoma) located in the pituitary gland, the 'conductor' of the body situated at the base of the brain, which excessively secretes the maternal hormone 'prolactin'.

Is It Cancer?

No, prolactinomas are not cancer (they are benign) and do not spread to other organs. Their main harm lies in disrupting hormone balance and, if they grow, putting pressure on the optic nerves.

What Are the Symptoms in Women?

High prolactin suppresses ovulation. The most typical symptoms are spontaneous milk discharge from the breasts (galactorrhea) despite not being pregnant or postpartum, menstrual delays or complete cessation of periods (amenorrhea), and infertility.

What Complaints Does It Cause in Men?

It lowers testosterone in men. Loss of sexual desire (decreased libido), erection problems (impotence), loss of beard and body hair, and sometimes breast enlargement are observed.

How is it Diagnosed?

Following an excessively high Prolactin level (usually well over 100) found in blood tests, a Pituitary MRI is performed to determine the millimeter-precise size of the tumor in the brain.

Is Surgery Mandatory?

Surgery is not required in 90% of tumors. When medications (pills) called Dopamine agonists (e.g., Cabergoline) are used, the tumor miraculously shrinks and dissolves within a few months, and the prolactin level returns to normal. Masses that do not respond to medication or crush the optic nerve enough to cause blindness are removed by entering through the nose (transsphenoidal surgery).

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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