General Information About Guillain-Barré Syndrome
Disease Details and Frequently Asked Questions
It is a rapid and progressive state of paralysis that begins when the immune system mistakenly attacks and destroys the outer sheath (myelin) of peripheral nerves following a simple infection.
The disease generally starts with tingling, a 'pins and needles' sensation, and weakness in the feet and legs. This weakness climbs upward (to the arms and trunk) within hours or days, turning into widespread muscle paralysis.
Yes. When the disease reaches the trunk and paralyzes the diaphragm and rib muscles (respiratory muscles), the patient is unable to breathe on their own and must be urgently admitted to intensive care and placed on a mechanical ventilator.
Although the paralysis develops very dramatically and quickly, with appropriate treatment, over 80% of patients completely or largely recover and return to their former health within a few months.
The loss of neurological reflexes suggests the diagnosis. For a definitive diagnosis, an EMG test that measures nerve conduction speed and the detection of elevated protein levels in the cerebrospinal fluid (CSF) obtained through a lumbar puncture are required.
Once the disease is confirmed, IVIG (intravenous immunoglobulin) serums that neutralize the faulty antibodies in the immune system, or Plasmapheresis procedures where the patient's blood is washed and cleaned in machines, are applied immediately.
Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.
