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Mitral Regurgitation

Diagnosis, symptoms, and treatment methods.

General Information About Mitral Regurgitation

Mitral regurgitation is a condition where the mitral valve, which acts as a one-way door between the left atrium and left ventricle of the heart, cannot close completely, causing oxygenated blood to leak backward (toward the lungs) during each ventricular contraction. It can cause heart failure, palpitations, and dyspnea. In our Cardiology and Cardiovascular Surgery departments, the degree of regurgitation is measured via echocardiography, and managed with medical follow-up or surgical valve repair/replacement.

Disease Details and Frequently Asked Questions

Detailed information regarding the disease can be accessed from the headings below.
What is Mitral Regurgitation?

With each contraction of the heart, blood should be pumped forward into the body; however, due to laxity or dysfunction of the valve between the chambers, a portion of the blood leaks backward into the chamber it came from (the left atrium), doubling the workload of the heart.

What Causes It?

Age-related valve calcification, childhood Rheumatic Heart Disease (Acute Rheumatic Fever), rupture of the chordae tendineae supporting the valve, myocardial infarctions, and genetic valve laxity (Mitral Valve Prolapse) are the most common causes.

What are its Symptoms?

In mild regurgitation, no symptoms may be observed for years. As the leak increases, symptoms include cardiac arrhythmias (Atrial Fibrillation/palpitations), easy fatigability, shortness of breath when climbing stairs, coughing, and orthopnea (dyspnea when lying flat at night).

How is it Diagnosed?

A 'murmur' (the sound of blood jetting backward) heard by a cardiologist while listening to the heart with a stethoscope raises suspicion. A definitive diagnosis and the exact millimetric volume of the regurgitation are determined via Echocardiography (ECHO - Heart Ultrasound).

Can a Heart Valve Recover with Medication?

There is no medication that can restore a damaged and deformed mechanical valve to its original state. Prescribed blood pressure and rhythm medications only alleviate symptoms temporarily by reducing the workload of the heart.

When is Surgery Mandatory?

If the regurgitation has progressed to a 'severe' degree, causing the heart to dilate and fluid to accumulate in the lungs, surgery is mandatory. Through open or minimally invasive (axillary/robotic) methods, the valve is preserved and reconstructed (repaired) using the patient's own tissue, or completely removed and replaced with a biological/mechanical prosthetic valve.

Our health library contents are prepared for informational purposes only and with scientific data available at the time of recording. For all your questions, concerns, diagnosis, or treatment regarding your health, please consult your doctor or a healthcare institution.


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