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Çakırtepe Hastanesi
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Prolotherapy

About the Treatment Method

Prolotherapy (Proliferative Therapy) is a non-surgical and alternative orthopedic/physical therapy method in which special irritating sugary (dextrose) solutions are injected into the damaged area in order to trigger the tissue's self-healing mechanism (regeneration) in chronic joint, tendon, and ligament injuries. It aims to re-tighten torn ligaments in cases such as unresolved neck and low back pains, cruciate ligament injuries, and tennis elbow.

Healing by Irritation (Regeneration)

The logic of sugary water waking up the body's repair cells.
How does sugary water heal tissue?

Blood flow (and healing) has stopped in torn or chronic connective tissue. When dense Dextrose (sugar) water is injected into that area, the body intentionally and controlledly initiates a "micro-inflammation" in that area. The brain says "there is a new damage there" and sends fibroblasts and reparative blood cells to that area. Thus, the ligaments thicken and get stronger by producing brand new collagen.

What is its difference from cortisone injections?

It is exactly the opposite. Cortisone injections instantly stop the pain by suppressing the inflammation (and therefore the repair process) in that area, but in the long run, they can weaken the ligament even more. Prolotherapy, on the other hand, deliberately creates inflammation (repair) in that area. For this reason, pain "increases" for the first few days after prolotherapy, and actual healing occurs permanently within weeks.

How many sessions does the treatment take?

Because it takes time for the tissue to renew itself, sessions are usually applied at 3 or 4-week intervals. A plan of 3 to 6 sessions in total is made depending on the healing response of the patient. During the treatment, the patient is forbidden to use anti-inflammatory (ibuprofen, etc.) painkillers because these drugs stop the intended healing inflammation.

The information on this page is for general health advice. Please consult specialized physicians for personalized treatment or advice.


You can find all the information regarding your treatment and hospital stay process in this section.

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