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Anti-TPO Test

General Information About the Test

Anti-TPO (Anti-Thyroid Peroxidase) is an antibody test used in the diagnosis of autoimmune thyroid diseases, which occur when the immune system mistakenly attacks the thyroid gland. It plays a key role, particularly in diagnosing Hashimoto's disease (thyroiditis), which causes an underactive thyroid, and Graves' disease, which causes an overactive thyroid.

Test Process and Preparation

Anti-TPO test measurement and patient preparations.
What does elevated Anti-TPO indicate?

A high level of Anti-TPO in the blood indicates that the immune system is damaging thyroid tissue (an autoimmune process). It is most frequently found to be elevated in Hashimoto's thyroiditis.

For which complaints is it requested?

It is requested alongside TSH and T4 tests when symptoms of thyroid dysfunction are observed, such as unexplained weight gain or loss, persistent fatigue, hair loss, and intolerance to cold or heat.

Does it require fasting or discontinuation of medication?

Fasting is not strictly necessary for the Anti-TPO test. However, since your doctor will likely request other thyroid hormones (like TSH) concurrently, it is generally recommended to have your blood drawn on an empty stomach in the morning. A physician should be consulted regarding the use of thyroid medications on the day of the test.

The information on this page is for informational purposes only. The results of medical tests must be evaluated by specialist physicians.


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