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Sedimentation

General Information About the Test

Sedimentation (Erythrocyte Sedimentation Rate - ESR) is a fundamental laboratory test that measures how quickly the red blood cells (erythrocytes) in blood drawn into a special tube settle to the bottom of the tube within one hour, measured in millimeters (mm/hour). It is a very old but still highly valuable marker used to detect inflammation in the body caused by any reason (infection, rheumatism, or cancer) and to monitor the course of diseases.

Test Process and Preparation

Measurement of sedimentation rate and evaluation of inflammation.
Why does sedimentation accelerate (increase)?

When there is inflammation in the body, special proteins like fibrin increase in the blood. These proteins cause the red blood cells to stick together, making them heavier and causing them to settle to the bottom of the tube much faster. This value increases during rheumatic flare-ups, infections, and pregnancy.

What is the difference from the CRP test?

Both are indicators of inflammation. However, while CRP responds to acute situations very quickly (within hours), Sedimentation rises much more slowly and can remain high even weeks after the disease has healed. The two tests are generally evaluated together.

What disease does elevated sedimentation indicate?

It is not a specific test. That is, it signals that there is "inflammation" in the body but does not tell whether it is caused by a throat infection, rheumatism, or another condition. Clinical findings are essential for diagnosis.

The information on this page is for informational purposes only. The results of medical tests must be evaluated by specialist physicians.


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