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Sentinel Lymph Node Biopsy

General Information About the Test

Sentinel Lymph Node Biopsy is the procedure in breast cancer or melanoma (skin cancer) surgery where the "sentinel" lymph node—the first lymph node to which the tumor might spread—is located, removed during surgery, and sent to pathology. If there are no cancer cells in this first lymph node, it prevents the unnecessary complete removal of the other lymph nodes in the armpit (and the risk of lymphedema, which is permanent swelling in the arm).

Test Process and Preparation

The application of the sentinel lymph node procedure during breast cancer surgery.
How is the sentinel lymph node found?

Just before or during the surgery, a blue dye and/or a very low-dose radioactive substance is injected around the tumor. This substance travels through the lymphatic channels and dyes the first (sentinel) lymph node into which the tumor drains. The surgeon locates and removes that node using a device.

What is the biggest benefit of the procedure to the patient?

In the past, during breast cancer surgeries, all the lymph nodes in the armpit were removed, which caused severe swelling (lymphedema) and restricted movement in the arm. Thanks to this method, if the cancer has not spread to the sentinel node, the other lymph nodes are preserved, and the patient's quality of life is improved.

When is the result known?

The removed lymph node is urgently sent to pathology using the "Frozen Section" method while the patient is still on the operating table. The result comes back in about 15-20 minutes, and the surgeon determines the course of the surgery based on this result.

The information on this page is for informational purposes only. The results of medical tests must be evaluated by specialist physicians.


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