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Thyroglobulin

General Information About the Test

Thyroglobulin (Tg) is a protein produced in the body solely by the thyroid gland and used in the production of thyroid hormones. A healthy thyroid gland continuously produces a small amount of thyroglobulin. However, the primary and most vital purpose of this test is as a "Tumor Marker" to detect at an early stage whether the tumor has recurred (relapsed) in patients being treated for Thyroid Cancer or those who have had their thyroid gland completely removed by surgery.

Test Process and Preparation

Measurement of the thyroglobulin level and cancer follow-up processes.
What should the Thyroglobulin level be after thyroid cancer surgery?

If the entire thyroid gland has been removed through successful cancer surgery or if radioactive iodine treatment has been received, the Thyroglobulin (Tg) level in the blood is expected to be very close to zero. If the value begins to rise over time, it is suspected that cancerous thyroid cells are growing again somewhere in the body (lymph node, lungs, etc.).

What is Anti-Thyroglobulin (Anti-Tg)?

It is an antibody produced by the immune system against thyroglobulin. If Anti-Tg is present in the blood, it masks the result of the Thyroglobulin test, causing it to appear falsely low. For this reason, the two tests are always evaluated together.

Should I give blood on an empty stomach?

Because the thyroglobulin test is not affected by food intake, strict fasting is not required. It is performed by drawing blood from an arm vein at any time of the day.

The information on this page is for informational purposes only. The results of medical tests must be evaluated by specialist physicians.


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