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VDRL Test

General Information About the Test

The VDRL (Venereal Disease Research Laboratory) Test is the most common and fundamental blood test used in the screening of "Syphilis," a sexually transmitted disease that can lead to brain, heart, and organ damage if left untreated. It is routinely requested in pre-marital health screenings, during the first months of pregnancy, and in individuals with a history of suspicious sexual contact.

Test Process and Preparation

Syphilis screening and laboratory test processes.
Does a positive VDRL test mean definitive syphilis?

No. The VDRL is a very sensitive screening test but is not 100% specific to the disease. It can yield a "False Positive" in conditions such as rheumatic diseases like Lupus, pregnancy, tuberculosis, and old age. If the result is positive, confirmatory tests such as TPHA or FTA-ABS must be performed for a definitive diagnosis.

How long after suspicious contact should it be tested?

It can take several weeks for the body to produce antibodies against the syphilis microbe (Treponema pallidum). Therefore, it yields the most accurate result when performed 3 to 6 weeks after a suspicious contact.

Is fasting mandatory for the blood test?

No. Because it is a test that looks for syphilis antibodies, it is not affected by eating food. It can be processed with blood drawn from an arm vein at any time of the day.

The information on this page is for informational purposes only. The results of medical tests must be evaluated by specialist physicians.


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